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特定助教

伏屋 康寛

Yasuhiro Fuseya

Message

LUBACやHOIL-1Lの機能解析とヒト疾患との関わりを研究しています。

Projects

Project
1

直鎖状ユビキチン鎖の機能解析

 Project
2

慢性炎症・がんにおける直鎖状ユビキチン鎖の役割

 Project
3

LUBAC機能制御薬の創成

 Project
4

細胞内鉄動態、フェロトーシスの解析

Publications

原著論文

The HOIL-1L ligase modulates immune signaling and cell death via mono-ubiquitination of LUBAC

Fuseya, Y., Fujita, H., Kim, M., Ohtake, F., Nishide, A., Sasaki, K., Saeki, Y., Tanaka, K., Takahashi, R. and Iwai, K.

Nature Cell Biology 22(6): 663-673, 2020. DOI

A Case of Adult-onset Repeat Rhabdomyolysis with a Very Long-chain Acyl-CoA Dehydrogenase Deficiency Due to Compound Heterozygous ACADVL Mutations.

Fuseya Y, Sakurai T, Miyahara JI, Sato K, Kaji S, Saito Y, Takahashi M, Nishino I, Fukuda T, Sugie H, Yamashita H

Intern. Med. 2020;59(21):2729-2732. DOI

Pembrolizumab-Induced Rhabdomyolysis With Myositis in a Patient With Lung Adenocarcinoma.

Hamada S, Fuseya Y, Tsukino M

Arch. Bronconeumol. 2018;54(6):346-8.

Transient Splenial Lesion Following Abrupt Withdrawal of Carbamazepine.

Fuseya Y, Komatsu K, Matsumoto S

Intern. Med. 2017;56(8):989-90.

rt-PA with Antithrombotic Therapies in a Case with Capsular Warning Syndrome.

Fuseya Y, Kawamura M, Matsuda E, Takada K, Watanabe K, Fujitake J, Nakaya Y

Intern. Med. 2017;56(4):441-4.

Insights from the ganglionic acetylcholine receptor autoantibodies in patients with Sjogren's syndrome.

Mukaino A, Nakane S, Higuchi O, Nakamura H, Miyagi T, Shiroma K, Tokashiki, T, Fuseya Y, , Ochi K, Umeda M, Nakazato T, Akioka S, Maruoka H, Hayashi M, Igarashi S, Yokoi K, Maeda Y, Sakai W, Matsuo H, Kawakami A

Mod. Rheumatol. 2016;26(5):708-15.

Interferon-beta may ameliorate synucleinopathy.

Fuseya Y, Takahashi R

Mov. Disord. 2016;31(4):497.

総説論文

免疫応答と細胞死を制御する直鎖状ユビキチン鎖の生成調節機構の解明とその応用

伏屋康寛、岩井一宏

臨床免疫・アレルギー科,75(6):730-736,2021

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