• HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.

    Magnani, N.D., Dada, D.A., Queisser, M,A., Brazee, P., Welch, L,C., Anekalla, K., Zhou, G., Misharin, A., Budinger, G.R.S., Iwai, K., Ciechanover, A.J., and Sznajder J.I.   

    
Proc. Natl. Acad. Sci. USA. 114(47):E10178-E10186, 2017. doi: 10.1073/pnas.1713563114.

 
                                                        
    
                                                    
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                                                            Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.
                                                        
    
                                                        
    
                                                            Yoshida, Y., Yasuda, S., Fujita, T., Hamasak,i M., Murakami, A., Kawawaki, J., Iwai, K., Saeki, Y., Yoshimori, T., Matsuda, N., and Tanaka, K.

    
Proc. Natl. Acad. Sci. USA. 114(32):8574-8579. 2017 Jul 25. pii: 201702615. doi: 10.1073/pnas.1702615114..
                                                        
    
                                                    
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                                                            HTLV-1 Tax induces formation of the active macromolecular IKK complex by generating Lys63- and Met1-linked hybrid polyubiquitin chains.
                                                        
    
                                                        
    
                                                            Shibata, Y., Tokunaga, F., Goto, E., Komatsu, G., Gohda, J., Saeki, Y., Tanaka, K., Takahashi, H., Sawasaki, T., Inoue, S., Oshiumi, H., Seya, T., Nakano, H., Tanaka, Y., Iwai, K., and Inoue, J.I.

    
PLoS Pathog. 13(1):e1006162. doi: 10.1371/journal.ppat.1006162, 2017.
                                                        
    
                                                    
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