• Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain Formation.

    Bowman, J., Rodgers, M.A., Shi, M., Amatya, R., Hostager, B., Iwai, K., Gao, S.J., and Jung, J.U.
    MBio. 6(6). pii: e01777-15, 2015.

  • The Structural differences between a glycoprotein specific F-Box protein Fbs1 and its homologous protein FBG3.

    Kumanomidou, T., Nishio, K., Takagi, K., Nakagawa, T., Suzuki, A., Yamane, T., Tokunaga, F., Iwai, K., Murakami, A., Yoshida, Y., Tanaka, K., and Mizushima, T.
    PLoS One 10(10):e0140366, 2015.

  • CYLD and the NEMO zinc finger regulate tumor necrosis factor signaling and early embryogenesis.

    Zhao, Y., Ma, C. A., Wu, L., Iwai, K., Ashwell, J. D., Oltz, E. M., Ballard, D. W., and Jain, A.
    J. Biol. Chem. 290(36):22076-22084, 2015.

  • LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

    Matsunaga, Y., Nakatsu, Y., Fukushima, T., Okubo, H., Iwashita, M., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kushiyama, A., Takahashi, S., Tsuchiya, Y., Kamata, H., Tokunaga, F., Iwai, K., and Asano, T.
    Mediators Inflamm. 2015:125380, 2015.

  • Potential biomarkers of fatigue identified by plasma metabolome analysis in rats.

    Kume, S., Yamato, M., Tamura, Y., Jin, G., Nakano, M., Miyashige, Y., Eguchi, A., Ogata, Y., Goda, N., Iwai, K., Yamano, E., Watanabe, Y., Soga, T., and Kataoka, Y.
    PLoS One 10(3):e0120106, 2015.

  • Phenotypic complementation of genetic immunodeficiency by chronic herpesvirus infection.

    MacDuff, D. A., Reese, T. A,, Kimmey, J. M., Weiss, L. A., Song, C., Zhang, X., Kambal, A., Duan, E., Carrero, J. A., Boisson, B., Laplantine, E., Israel, A., Picard, C., Colonna, M., Edelson, B. T., Sibley, L. D., Stallings, C. L., Casanova, J. L., Iwai, K., Virgin, H. W.
    eLife 4:e04494. doi: 10.7554/eLife.04494, 2015.

  • The unexpected role of polyubiquitin chains in the formation of fibrillar aggregates.

    Morimoto, D., Walinda, E., Fukada, H., Sou, Y. S., Kageyama, S., Hoshino, M., Fujii, T., Tsuchiya, H., Saeki, Y., Arita, K., Ariyoshi, M., Tochio, H., Iwai, K., Namba, K., Komatsu, M., Tanaka, K., Shirakawa, M.
    Nature Commun. 6:6116. doi: 10.1038/ncomms7116, 2015.

  • Gliotoxin Suppresses NF-κB Activation by Selectively Inhibiting Linear Ubiquitin Chain Assembly Complex (LUBAC).

    Sakamoto, H., Egashira, S., Saito, N., Kirisako, T., Miller, S., Sasaki, Y., Matsumoto, T., Shimonishi, M., Komatsu, T., Terai, T., Ueno, T., Hanaoka, K., Kojima, H., Okabe, T., Wakatsuki, S., Iwai, K.,  (coreesonding author) and Nagano, T.
    ACS Chem Biol. 10:675-681, 2015.

  • Possible involvement of iron-induced oxidative insults in neurodegeneration.

    Asano, T., Koike, M., akata, S.-I., Takeda, Y., Nakagawa, T., Hatano, T., Ohashi, S., Funayama, M., Yoshimi, K., Asanuma, M., Toyokuni, S., Mochizuki, H., Uchiyama, Y., Hattori, N., and  Iwai, K.
    Neurosci. Lett. 588:29-35, 2015.