Publications

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

Fujita, N., Morita, E., Itoh, T., Tanaka, A., Nakaoka, M., Osada, Y., Umemoto, T., Saitoh, T., Nakatogawa, H., Kobayashi, S., Haraguchi, T., Guan, J.L., Iwai, K., Tokunaga, F., Saito, K., Ishibashi, K., Akira, S., Fukuda, M., Noda, T., and Yoshimori, T.

J. Cell Biol. 203:115-128, 2013.

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

Sasaki, Y., Sano, S., Nakahara, M., Murata, S., Kometani, K., Aiba, Y., Sakamoto, S., Watanabe, Y., Tanaka, K., Kurosaki, K. and Iwai, K.

EMBO J. 32: 2463- 2476, 2013.

IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway.

Seki, M., Takeda, Y., Iwai, K., and Tanaka, K.

J. Biol. Chem. 288:16680-16689, 2013.

Two coordinated mechanisms underlie TNFα-induced immediate and delayed IKK activation.

Blackwell, K., Zhang, L., Workman, L.M., Ting, A.T., Iwai, K., Habelhah, H.

Mol. Cell. Biol. 33:1901-1915, 2013.