Publications


Differential involvement of LUBAC-mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation

Sakamoto Y, Sasaki K, Omatsu M, Hamada K, Nakanishi Y, Itatani Y, Kawada K, Obama K, Seno H, Iwai K.

The Journal of Pathology. 2023 Mar;259(3):304-317. doi: 10.1002/path.6042. Epub 2022 Dec 20. PMID: 36454102 DOI

Genetic deletion and pharmacologic inhibition of E3 ubiquitin ligase HOIP impairs the propagation of myeloid leukemia

Jimbo K, Hattori A, Koide S, Ito T, Sasaki K, Iwai K, Nannya Y, Iwama A, Tojo A, Konuma T.

Leukemia. 2023 Jan;37(1):122-133. doi: 10.1038/s41375-022-01750-7. Epub 2022 Nov 9. DOI

HOIL1 regulates group 2 innate lymphoid cell numbers and type 2 inflammation in the small intestine

Wood MJ, Marshall JN, Hartley VL, Liu TC, Iwai K, Stappenbeck TS, MacDuff DA.

Mucosal Immunol. 2022 Apr;15(4):642-655. doi: 10.1038/s41385-022-00520-z. Epub 2022 May 9. DOI

Iron-induced NCOA4 condensation regulates ferritin fate and iron homeostasis

Kuno, S., Fujita, H., Tanaka, Y., Ogra, Y. and Iwai, K.

EMBO rep. 2022 May 4;23(5):e54278. DOI

ABIN1 is a signal-induced autophagy receptor that attenuates NF-kappaB activation by recognizing linear ubiquitin chains

Shinkawa, Y., Imami, K., Fuseya, Y., Sasaki, K., Ohmura, K., Ishihama, Y., Morinobu, A., Iwai, K.

FEBS Lett. 2022 May;596(9):1147-1164. DOI

Glycogen synthase downregulation rescues the amylopectinosis of murine RBCK1 deficiency

Nitschke, S., Sullivan, M.A., Mitra, S., Marchioni, C.R., Lee, J.P.Y., Smith, B.H., Ahonen, S., Wu, J., Chown, E.E., Wang, P., Petković, S., Zhao, X., DiGiovanni, L.F., Perri, A.M., Israelian, L., Grossman, T.R., Kordasiewicz, H., Vilaplana, F., Iwai, K., Nitschke, F., Minassian, B.A.

Brain 2022 Jul 29;145(7):2361-2377. DOI