Publications

HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.

Magnani, N.D., Dada, D.A., Queisser, M,A., Brazee, P., Welch, L,C., Anekalla, K., Zhou, G., Misharin, A., Budinger, G.R.S., Iwai, K., Ciechanover, A.J., and Sznajder J.I

Proc. Natl. Acad. Sci. USA. 114(47):E10178-E10186, 2017. doi: 10.1073/pnas.1713563114. DOI

Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.

Yoshida, Y., Yasuda, S., Fujita, T., Hamasak,i M., Murakami, A., Kawawaki, J., Iwai, K., Saeki, Y., Yoshimori, T., Matsuda, N., and Tanaka, K.

Proc. Natl. Acad. Sci. USA 114(32):8574-8579. 2017 Jul 25. pii: 201702615. DOI

HTLV-1 Tax induces formation of the active macromolecular IKK complex by generating Lys63- and Met1-linked hybrid polyubiquitin chains.

Shibata, Y., Tokunaga, F., Goto, E., Komatsu, G., Gohda, J., Saeki, Y., Tanaka, K., Takahashi, H., Sawasaki, T., Inoue, S., Oshiumi, H., Seya, T., Nakano, H., Tanaka, Y., Iwai, K., and Inoue, J.I.

PLoS Pathog. 13(1):e1006162, 2017. DOI